Arch Iran Med
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Biography Historical Article
Dr. Hossein Malekafzali: A Pioneer in Iran's Health Evolution and Development.
Dr Malekafzali, an elite biostatistics professor at Tehran University of Medical Sciences, in his more than 50 years of glorious service, has played a crucial role in creation of fundamental evolution in public health, reproductive health and development of applied research in Iran. He has left lasting activities in administrative positions such as health and research deputies, health minister consultant, director of health faculty and director of health research institutes. He published several books and articles on statistics, epidemiology and public health. This article is a review of his worthy and interesting activities in the country's health, research and education.
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Aichi virus (AiV) is an emerging virus, which belongs to Kobuvirus genus of the Picornaviridae family. AiV was recently determined as an etiologic agent of gastroenteritis in susceptible humans. After shedding of virus particles from affected people, AiV particles can contaminate water sources. Then, infection with this virus occurs in humans by the fecal-oral route after exposure with contaminated waters. Thus far, some research around the world demonstrated that different kinds of water sources including river water, ground water and treated or untreated sewage water have contamination with AiVs. Molecular detection of AiV has been mostly depended on reverse transcription polymerase chain reaction (RT-PCR) methods, which targeted 3CD junction region of the virus genome. ⋯ Our results, for the first time, indicate that AiVs have been circulating in Iran.
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Mean platelet volume (MPV) has been introduced as a simple and accurate method for assessing platelet function, which can be used as a prognostic marker for cardiovascular events. We investigated whether pre-procedural MPV could predict major adverse cardiac events (MACE) in candidates for elective percutaneous coronary intervention (PCI). ⋯ High MPV was associated with cardiovascular risk factors and older age while high MPV was a borderline independent predictor for 1-year MACE in the candidates for elective PCI.
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Case Reports
A Rare Case of Takayasu's Arteritis with Aortic Arch Branching Pattern Variation in a Young Female.
Takayasu's arteritis, formerly known as "pulseless disease", is a chronic inflammatory disease which affects the aorta and its main branches. The prevalence of this disease is higher in Asian countries and among young women. Depending on the progress of the disease, the symptoms and prognosis of the disease is different. ⋯ In addition, an anatomic variation was observed in the aortic arch branches. In this patient, the left vertebral artery was branched directly from the aortic arch instead of the left subclavian artery. Hepatomegaly and splenomegaly, indicating a chronic inflammatory disease, were also observed in this case.