Arch Iran Med
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Randomized Controlled Trial Comparative Study
Antioxidative effects of propofol vs. ketamin in individuals undergoing surgery.
Propofol (2, 6-diisopropylphenol) is a widely used intravenous sedative-hypnotic agent for both induction/maintenance of anesthesia and sedation of critically ill patients. The present study aimed to evaluate oxidative stress biomarkers in individuals undergoing surgery with propofol and ketamine at doses used to induce anesthesia. ⋯ In conclusion, our findings showed that propofol has antioxidant effects in human. Further studies need to be conducted to demonstrate the exact mechanism of oxidative stress caused by anesthesia in surgery patients.
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Hospitalized patients constitute the main fraction of users in any health system. Financial burden of reimbursement for received services and cares by these users is sometimes unbearable and may lead to catastrophic medical payments. So, designing and implementing effective health prepayments schemes appear to be an effective governmental intervention to reduce catastrophic medical payments and protect households against it. We aimed to calculate the proportion of hospitalized patients exposed to catastrophic medical payments, its determinant factors and its distribution. ⋯ There is a high level of catastrophic medical payments in hospitalized patients. The weakness of economic status of households and the not well designed prepayments schemes on the other hand may lead to this. This paper illustrated a clear picture for catastrophic medical payments at hospital level and suggests applicable notes to Iranian health policymakers and planners.
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Atherosclerosis is the main cause of death in the world through causing ischemic heart disease (IHD). Altered serum lipid level is the most important risk factor for coronary artery disease (CAD). Many studies reveal a strong inverse association between low levels of high density lipoprotein cholesterol (HDL-C) and increased risk of IHD. ⋯ Other potentially important candidates involved in low HDL-C syndromes are metabolic disorders including sphingomyelin phosphodiesterase 1 and glucocerebrosidase. Also Molecular variations in many genes such as ABCAI and APOAI, TRIB1 and Apo E, lipoprotein lipase (LPL), WW domain-containing oxidoreductase (WWOX), Hepatic lipase (HL), lecithin cholesteryl acyl transferase and some linkage analysis have been associated with reduced HDL-Status. Low HDL-C syndrome has a strong genetic basis and is correlated with an increased risk of CAD.
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Consumption of white rice has been proposed as a dietary risk factor for development of metabolic disorders and type 2 diabetes, especially in populations who consume white rice as a staple food. In this study, we investigated the association between consumption of white rice and the occurrence of metabolic syndrome in Tehrani adults after 3 years of follow-up. ⋯ We demonstrated that higher consumption of white rice may be a risk factor for development of metabolic syndrome among Iranian adults.
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There is no comprehensive report on seasonal variations in individuals' blood pressure (BP) in Iranian subjects. The aim of this study is to evaluate individuals' BP during the four seasons of the year in a large number of adults in Tehran. In a population-based study in Tehran, over a period of ten years (from 1998 to 2011) during the follow up of the four phases of the TLGS, data from a total of 29777 participants aged 20-80 years (42.29% male and 57.71% female) were collected. ⋯ The difference between mean SBP in winter and spring and the difference of mean DBP in winter and summer were near significance level (P = 0.058 and 0.086, respectively). Compared to summer and spring, the individuals' SBP was higher during winter and their DBP in winter was also higher compared to summer. More attention should be paid to BP measurement in epidemiological studies.