B Acad Nat Med Paris
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B Acad Nat Med Paris · Dec 2020
Review[From the bench to the clinic: The challenge of translating platelet production in vitro].
Platelet transfusions, which are currently totally dependent on altruistic donations, are absolutely necessary to the treatment of patients with thrombocytopenia following trauma, surgery or other pathologies (especially malignancies). Producing platelets in vitro represent a major technological and scientific breathrough that would address logistical issues (supply chain, stock holding…) and medical concerns (compatibility and biosafety). The translation of this innovation will need to be accompanied by rigorous quality control, harmonised between laboratory when it comes to functionality and biosafety for use in the clinic.
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Seafood could be a solution to meet global food demand that will double by 2050. Seafood includes a wide variety of edible marine organisms, except fish and mammals. These are molluscs, crustaceans, echinoderms and algae. ⋯ Finally, the dietary habits of seafood favour exposure to certain hazards. Seafood safety must be integrated throughout the food chain, under the responsibility shared by all stakeholders. Seafood safety appears to be an emerging public health issue of global scope, because the sea does not stop at borders.