Bratisl Med J
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The present work aimed to study the efficacy and patient compliance of oral theophylline treatment in the prevention of vasovagal syncope recurrences. ⋯ The addition of oral theophylline preparation to non-pharmacological treatment led to a marked reduction of syncopal recurrence in patients with vasovagal syncope. About one-third of study subjects discontinued therapy because of side effects (Tab. 2, Fig. 4, Ref. 22). Text in PDF www.elis.sk Keywords: heophylline, adenosine, vasovagal syncope, treatment.
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Slovakia, in accordance with a global trend, is experiencing an increasing cancer burden. Development and assessment of preventive and healthcare interventions are informed by cancer epidemiology. This study presents the current epidemiological situation and trends for three prevalent malignancies: breast, colorectal, and cervical cancer in the Slovakia. ⋯ Despite progress in specific areas of cancer care, Slovakia acknowledges the need for further improvements. Enhancing cancer screening uptake presents a crucial area for advancement (Fig. 7, Ref. 19). Keywords: epidemiology, Slovakia, breast cancer, colorectal cancer, cervical cancer.
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Traditionally, astrocytes are categorized into fibrous and protoplasmic types based on their morphological appearance. ⋯ Our immunohistochemical study demonstrates that GFAP-positive cells with morphology similar to protoplasmic astrocytes rarely occur in injured brain cortex. We conclude that brain tissue contains GFAP-negative glial precursor cells, which can differentiate into GFAP-positive cells under pathological conditions and sometimes exhibit protoplasmic or intermediate morphology. Similarly, GFAP staining is increased in fibrous astrocytes, typically described as reactive to brain noxa. These results raise many questions about astrocytes identification and classification. In addition, these findings may explain the absence of GFAP-positive cells in adult human brain cultures, often termed "glia-like" cells (Fig. 3, Ref. 18).