Chinese Med J Peking
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Chinese Med J Peking · Oct 2003
Clinical features of pheochromocytoma and perioperative anesthetic management.
To investigate clinical features of pheochromocytoma and summarize experiences of anesthetic management during the perioperative period. ⋯ A positive surgical outcome of the excision of pheochromocytoma depends on multiple factors, including careful assessment of potential vital organ damage before surgery and restoration of blood volume by establishing alpha-blockade preoperatively, meticulous anesthetic management of patients during surgery, and appropriate circulatory support after surgery.
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Chinese Med J Peking · Oct 2003
Vascular endothelial growth factor gene transfection to enhance the repair of avascular necrosis of the femoral head of rabbit.
To explore a new method for the therapy of avascular necrosis of the femoral head. ⋯ Transfection of the VEGF gene enhances bone tissue angiogenesis. Repair of osteonecrosis could be accelerated accordingly, thus providing a potential method for therapy of osteonecrosis.
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To evaluate the status of eight RHD specific exons in 131 Han Chinese blood donors who were classified as RhD-negative by serological methods and explore the genomic structure of RHD gene among the Han Chinese. The Rh blood group system has the highest prevalence of polymorphisms among human blood group systems and is clinically significant in transfusion medicine. The Rh antigens are expressed on polypeptides encoded by two highly homologous genes, RHD and RHCE. Recent molecular studies have shown that the RhD-negative trait could be generated by multiple genetic mechanisms and is ethnic group-dependent. ⋯ Three classes of RhD-negative polymorphisms among a population of Han Chinese were observed. Antigen association analysis suggested the existence of a novel class of RhD-negative associated haplotype in Han Chinese. This haplotype consisted of a normal RHCE allele and a nonfunctional RHD gene. It may be beneficial to redefine the RhD-negative blood group among Chinese populations upon clarification of the mechanisms of RHD gene expression and RhD antigen immunization.
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To investigate the effects of injecting Shenfu, an extract of traditional Chinese herbal medicines, on the central nervous system (CNS) and the cardiac toxicity of bupivacaine in rats. ⋯ The Shenfu injection is able to reduce the toxicity of bupivacaine to CNS and cardiac system in rats.
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Chinese Med J Peking · Sep 2003
Randomized Controlled Trial Comparative Study Clinical TrialComparison of remifentanil and fentanyl in patients undergoing modified radical mastectomy or total hysterectomy.
To compare the efficacy and safety of remifentanil and fentanyl in patients undergoing a modified radical mastectomy or total hysterectomy. ⋯ Under the condition of this study protocol, the anesthetic and analgesic effects of remifentanil are more potent than those of fentanyl. Remifentanil can offer superior intraoperative hemodynamic stability in comparison with fentanyl, and has no compromising recovery from anesthesia.