Clin Med
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Erectile dysfunction (ED) affects millions of men worldwide with implications that go far beyond sexual activity. ED is now recognised as an early marker of cardiovascular disease, diabetes mellitus (DM) and depression. ⋯ Nevertheless, ED is commonly missed when evaluating patients in the hospital setting, either because of lack of consideration or awareness, or through simple embarrassment (of both clinician and patient). This article provides an overview of the aetiology, assessment and importance of ED and hopes to promote its consideration in day-to-day clinical practice.
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Recent years have seen several advances in the management of endocrine diseases. These include novel drugs developed as a consequence of better understanding of the pathophysiology of endocrine conditions, as well as improved delivery methods for existing drugs. In this article, we summarise recent studies evaluating several drugs used in the treatment of endocrine disorders.
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Panton-Valentine leukocidin is a cytotoxin produced by Staphylococcus aureus. It was initially discovered by Van deVelde in 1894 due to its ability to lyse leukocytes. ⋯ Panton and Valentine described this strain of S. aureus as a non-life-threatening, soft-tissue infection that caused recurrent furunculosis and abscesses; however, it is currently implicated in more serious and invasive infections in children and young healthy adults. This paper presents a case of the most fatal of these infections: necrotising haemorrhagic pneumonia.