Cochrane Db Syst Rev
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Cochrane Db Syst Rev · Jul 2007
ReviewWITHDRAWN: Selective serotonin reuptake inhibitors (SSRIs) versus other antidepressants for depression.
The relatively new class of antidepressant, the selective serotonin reputake inhibitors (SSRIs), may be better tolerated than the older tricyclic antidepressants. This review compares the efficacy of SSRIs with other antidepressants. ⋯ There are no clinically significant differences in effectiveness between selective serotonin reuptake inhibitors and tricyclic antidepressants. Treatment decisions need to be based on considerations of relative patient acceptability, toxicity and cost.
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Cochrane Db Syst Rev · Jul 2007
ReviewInfluenza vaccine for children and adults with bronchiectasis.
Bronchiectasis is a major cause of respiratory morbidity especially in developing countries. In affluent countries, bronchiectasis is increasingly recognised in certain subsections of communities (e.g. Aboriginal communities) as well as a coexistent disease/comorbidity and disease modifier in respiratory diseases such as COPD (reported rates of 29-50% in adults). Respiratory exacerbations in people with bronchiectasis are associated with reduced quality of life, accelerated pulmonary decline, hospitalisation and even death. Current recommendations for inactivated influenza vaccination includes adults aged 65 years and over, those in residential care and health care workers and also all adults and children with chronic illness, particularly cardiac and pulmonary diseases. ⋯ There is neither evidence for, nor against, routine annual influenza vaccination for children and adults with bronchiectasis.
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Cochrane Db Syst Rev · Jul 2007
ReviewWITHDRAWN: Cytomegalovirus prophylaxis with antiviral agents for solid organ transplantation.
Cytomegalovirus (CMV) disease is a major cause of morbidity and mortality in solid organ transplantation. It is also associated with an increased risk of opportunistic infections, allograft injury and higher transplantation costs. CMV infection also seems to increase the risk of acute and chronic rejection of allografts via immune-mediated vascular injury. These serious consequences of CMV disease have lead to the development of effective strategies for the prevention, early diagnosis and treatment. However, there is no consensus on the necessity and the efficacy of CMV prophylaxis. ⋯ The use of antiviral agents for the prevention of cytomegalovirus disease and cytomegalovirus infection in solid organ transplantation is supported by this meta-analysis.
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Cochrane Db Syst Rev · Jul 2007
Retracted PublicationWITHDRAWN: Effect of antihypertensive drugs on mortality, morbidity and blood pressure in blacks.
Black people have a greater prevalence of elevated blood pressure leading to excess morbidity and mortality. ⋯ When first-line drugs from different classes are compared in the treatment of black people, there is no evidence of differential effects on most mortality and morbidity outcomes. Those morbidity differences that were found favoured diuretics. Drugs differ in their ability to reduce blood pressure in black people. Calcium blockers were the only drug class that reduced blood pressure in all subgroups of black people including those with severe hypertension. Beta-blockers, angiotensin receptor blocker, alpha blockers and ACE Inhibitors were least good at reducing blood pressure in black adults.
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Cochrane Db Syst Rev · Jul 2007
ReviewExercise for treating anterior cruciate ligament injuries in combination with collateral ligament and meniscal damage of the knee in adults.
The anterior cruciate ligament (ACL) is the most frequently injured ligament of the knee. The ACL may be damaged in isolation but often other ligaments and menisci are implicated. The injury may be managed surgically or conservatively. Injury causes pain, effusion and inflammation leading to alteration in muscle function. Regaining muscular control is essential if the individual wishes to return to pre-injury level of function and patients will invariably be referred for rehabilitation. ⋯ This review has demonstrated an absence of evidence to support one form of exercise intervention over another. Further research should be considered in the form of large scale well-designed and well-reported randomised controlled trials with suitable outcome measures and surveillance periods. Suitable outcome measures should include a measure of functional outcome relevant to the individual.