Cochrane Db Syst Rev
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Huperzine A, a form of herbal medicine, has been considered as an alternative treatment for vascular dementia (VaD) in China. ⋯ There is no [convincing] evidence that Huperzine A is of value in vascular dementia based on one small trial. It deserves further research.
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Cochrane Db Syst Rev · Apr 2009
Review Meta AnalysisOsteotomy, compression and other modifications of surgical techniques for internal fixation of extracapsular hip fractures.
Many different surgical techniques have been described for the internal fixation of extracapsular hip fractures. ⋯ There is inadequate evidence to support the use of osteotomy for internal fixation of a trochanteric hip fracture. Similarly, there is insufficient evidence to support the use of the other techniques examined in the trials included in this review.
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Cochrane Db Syst Rev · Apr 2009
Review Meta AnalysisStimulation of the wrist acupuncture point P6 for preventing postoperative nausea and vomiting.
Postoperative nausea and vomiting (PONV) are common complications following surgery and anaesthesia. Drugs to prevent PONV are only partially effective. An alternative approach is to stimulate the P6 acupoint on the wrist. This is an update of a Cochrane review first published in 2004. ⋯ P6 acupoint stimulation prevented PONV. There was no reliable evidence for differences in risks of postoperative nausea or vomiting after P6 acupoint stimulation compared to antiemetic drugs.
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Cochrane Db Syst Rev · Apr 2009
Review Meta AnalysisMale circumcision for prevention of heterosexual acquisition of HIV in men.
Male circumcision is defined as the surgical removal of all or part of the foreskin of the penis and may be practiced as part of a religious ritual, as a medical procedure, or as part of a traditional ritual performed as an initiation into manhood. Since the 1980s, over 30 observational studies have suggested a protective effect of male circumcision on HIV acquisition in heterosexual men. In 2002, three randomised controlled trials to assess the efficacy of male circumcision for preventing HIV acquisition in men commenced in Africa. This review evaluates the results of these trials, which analysed the effectiveness and safety of male circumcision for preventing acquisition of HIV in heterosexual men. ⋯ There is strong evidence that medical male circumcision reduces the acquisition of HIV by heterosexual men by between 38% and 66% over 24 months. Incidence of adverse events is very low, indicating that male circumcision, when conducted under these conditions, is a safe procedure. Inclusion of male circumcision into current HIV prevention measures guidelines is warranted, with further research required to assess the feasibility, desirability, and cost-effectiveness of implementing the procedure within local contexts.
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Cochrane Db Syst Rev · Apr 2009
Review Meta AnalysisSingle dose oral diclofenac for acute postoperative pain in adults.
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), available as a potassium salt (immediate-release) or sodium salt (delayed-release). This review updates an earlier review published in The Cochrane Database of Systematic Reviews (Issue 2, 2004) on 'Single dose oral diclofenac for postoperative pain'. ⋯ Oral diclofenac is an effective single-dose treatment for moderate to severe postoperative pain. Significantly more participants experienced at least 50% pain relief over 4 to 6 hours with diclofenac potassium than with diclofenac sodium. There was no significant difference between diclofenac and placebo in the incidence of adverse events.