Dan Med Bull
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Extant literature shows that women having undergone breast cancer surgery have substantial problems at the post-anaesthesia care unit (PACU). Based on nursing reports and elements of the discharge scoring system recommended by The Danish Society of Anaesthesiology and Intensive Care Medicine, the present prospective, observational study aims to determine why these patients stayed at PACU. ⋯ Low SpO2 (< 90%), the workload at the PACU and time spent waiting for transport to the ward were the primary reasons why patients stayed at the PACU after breast cancer surgery.
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Sparse information with regard to the electrocardiographic (ECG) changes in Takotsubo cardiomyopathy (TC) is available. The purpose of this study was to describe the clinical characteristics and electrocardiographic changes in a Danish cohort of patients with TC. We discuss the potential pathophysiological mechanisms of TC. ⋯ In the acute phase symptoms and ECG changes resemble those in patients with STEMI, hence acute coronary angiography is indicated in most cases. Pathophysiological aspects are discussed.
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Chronic uremia is characterized by decreased levels of plasma 1,25(OH)2D3 due to decreased renal 1-hydroxylase activity and by decreased renal phosphate excretion. The consequence is an increased synthesis and secretion of parathyroid hormone--secondary hyperparathyroidism--due to the low levels of plasma calcium, low levels of plasma 1,25(OH)2D3 and high levels of phosphate. The association between renal bone disease and chronic renal failure is well described. ⋯ There is now a general agreement on the importance of carefully controlling plasma phosphate, normalize and avoid increases of plasma Ca 2+, and not to oversuppress PTH during treatment. Focus today is on the potential deleterious role of calcium overloading in the development of vascular calcifications in uremic patients. There is an urgent need for a development of an algorithm for the use of phosphate binders and vitamin D supplementation in combination with calcimimetics focusing upon long term morbidity and mortality in uremic patients.
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In this study we tested how a combination of early and late paraclinic markers could predict early onset neonatal sepsis (EONS). ⋯ IL-6 combined with PCT values is a fair way to evaluate EONS at the time of suspicion of infection. The "old" early marker, I/T ratio, is almost as efficient as IL-6. By combining an early and a late marker it may be possible to reduce the diagnostic "non-conclusive" period of paraclinic values.
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Solar ultraviolet radiation (UVR) is known to be the most important etiological factor in skin cancer development. The main objective of this thesis was to achieve an objective, basic knowledge of the individual UVR exposure dose pattern and to reveal the factors and with which power they influence on the UVR dose among the Danes. Eight open prospective, observational studies and one study analyzing the compliance and reliability of data were performed in healthy Danish volunteers with an age range of 4-68 years. ⋯ Conclusions : - High UVR doses are connected with risk behaviour. Reduction of cumulative lifetime UVR dose could be obtained by minimizing risk behaviour. - Sunburns were highly correlated to risk behaviour. - Use of sunscreen correlated with days "sunbathing with the intention to tan", indicating that sunscreens were used to avoid sunburn during risk behaviour. - Scheduling lunch breaks and other breaks indoors at noon, where ambient UVR peaks, could reduce the occupational UVR exposure significantly. - In the winter-half-year in Denmark. the UVR dose received from solar exposure is negligible and no UVR precautions are needed. This study documented that high subject compliance rate and data reliability could be obtained in long-time UVR dosimeter study as ours by being service minded but persistent, offering dosimeter maintenance service within 24 hours and scrutinizing data for errors and mistakes just after data collection.