Dan Med Bull
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The objective of the study was to evaluate neonatal survival and subsequent disabilities in infants with extremely low gestational age in relation to perinatal events and neonatal treatment. A retrospective follow-up study was performed based on medical records, questionnaires to parents and recordings of contact with health authorities. All infants with a gestational age 28 completed weeks or less, who were admitted to the Department of Neonatology, Rigshospitalet, within 24 hours of age during the period January 1, 1987 - December 31, 1990 were included. ⋯ Sixty infants (31%) needed medical or surgical closure of a persistent ductus arteriosus. In 11 infants (6%) cystic periventricular leucomalacia occurred, 10 infants (5%) developed retinopathy of prematurity stage 3-4, and 35 infants (24%) received supplementary oxygen at 28 days of age. Risk factors present at birth for adverse outcome were: Apgar score <7 at five minutes, birth weight <1000 g, male sex and birth in another hospital than Rigshospitalet, For adverse outcome in surviving infants only, ICH grade II-IV was the only significant risk factor.
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Eight articles including 555 low back pain patients have been published. They included the following topics: 1) A ratio interval rating scale (Low Back Pain Rating Scale (RS)) was introduced. The possibility of registering the actual status in low back pain patients including; Back Pain, Sciatica, Functional Disability and Physical Impairment was studied. ⋯ The exercise programmes are generally free of side-effects. As regards chronic back pain patients with or without previous lumbar surgery, high dosage exercises with training periods lasting at least 12 to 16 sessions are of crucial importance for success. Exercises should be dynamic and full-range, and carried out following the adage "Don't let the pain be your guide.
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Review Comparative Study
The brain dopaminergic system. Pharmacological, behavioural and electrophysiological studies.
The kindling phenomenon is a good example of the effect of multiplicity on response increment processes in the nervous system. The electrical potentiation resembles pharmacological sensitization. An intermittent regimen is essential for a progressive augmentation of the behavioural response in both conditions. ⋯ Intermittent electrical activation of the cells in the VTA resulted in a syndrome characterized by a hypersensitive response to electrical or pharmacological dopaminergic provocation combined with abnormal social interactions. This new animal model may have implications for the understanding of the pathogenesis of schizophrenia. Hypotheses are proposed for the meaning of dopaminergic sensitization both in the development of persisting dyskinetic side-effects related to neuroleptic treatment and in the development of schizophrenia.
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Randomized Controlled Trial Comparative Study Clinical Trial
Anesthesia related hypoxemia. The effect of pulse oximetry monitoring on perioperative events and postoperative complications.
The objectives of the present investigation were to evaluate the extent of perioperative hypoxemia and to investigate the impact of pulse oximetry monitoring on the extent of hypoxemia and on perioperative morbidity in adults. To accomplish these objectives a number of prospective studies were carried out. The incidence, duration, and severity of hypoxemia were evaluated in two single blinded observer studies in the operating room (N = 296) (I) and in the Postanesthesia Care Unit (N = 200) (II). ⋯ Several changes in PACU care were observed in association with the use of pulse oximetry. These included higher flow rates of supplemental oxygen (P < 0.00001), increased use of supplemental oxygen at discharge (P < 0.00001), and increased use of naloxone (P < 0.02). One or more postoperative complications occurred in 10% of the patients in the oximetry group and in 9.4% in the control group (NS).(ABSTRACT TRUNCATED AT 400 WORDS)