Gac Med Mex
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Diagnosing and treating human immunodeficiency virus carriers has led to the identification of a higher prevalence of said infection and, therefore, of a higher risk of transmission of the virus. ⋯ Our results suggest that the human immunodeficiency epidemic in patients cared for at the Instituto Mexicano del Seguro Social is concentrated in males, with a growing trend particularly in adolescents.
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Head and neck cancer patients are at high risk of SARS-CoV-2 infection; surgery in them involves risk for patients, surgeons, health personnel, medical institutions and society, since it is associated with prolonged and inadvertent production of aerosols and emergency procedures that facilitate the breach of protective measures by health personnel. ⋯ Chest tomography is not useful as the only preoperative screening procedure for COVID-19, since its findings are nonspecific, with a high rate of false-positive results. Clinical evaluation, with PCR and tomography, is the best form of preoperative screening.
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Cardiomyocytes have a biochemical machinery with the capacity to synthesize, utilize and reuptake serotonin. ⋯ This study demonstrated an increased expression of TPH, SERT and SRs in cardiomyocytes from hearts with HCM in comparison with controls, which could be involved in the pathophysiology of HCM in humans.
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Population-specific reference ranges for uterine artery (UtA) mean pulsatility index (PI) throughout pregnancy have been shown to be of value in antenatal care. ⋯ UtA mean PI usually decreases according to placentation and maternal adaptation to pregnancy. The effects of parity on blood pressure and UtA mean PI might reflect cardiovascular remodeling after gestation.
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Diabetes mellitus (DM) inhibits brain serotonin biosynthesis through changes in tryptophan-5-hydroxylase (TPH) activity and expression. ⋯ DM chronically inhibits the synthesis of brain 5-hydroxytryptamine through changes in TPH1 and TPH2 expression and a decrease in the number of serotonergic neurons, which persist despite insulin treatment.