Gac Med Mex
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Observational Study
Knowledge and attitudes towards organ donation in a sample of physicians from two hospitals in Mexico.
For many patients, organ transplantation is the only life-saving treatment. There is a severe shortage of organs for transplantation, and Mexico has one of the lowest organ donation rates. Health professionals are the link between society and the health system, and can promote and increase organ donation. ⋯ It is necessary to implement programs aimed at physicians in order to provide them with tools that help promote organ donation culture.
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Neonates with congenital heart disease can develop neurological problems, which is why it is important to know the time and extent at which these lesions occur in order to elucidate their causes and implications. ⋯ There are various risk factors for neurological damage in patients with complex congenital heart disease, which is impossible to be entirely controlled. This study allows us to know, for the first time in our milieu, the changes in the central nervous system that could exist in these patients.
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Dendritic cells (DC) are involved in immune recognition, response and immunomodulation mechanisms related to the onset of cancer. ⋯ DCs can regulate autophagy in hepatocellular carcinoma cells. The mechanism may be related to the synthesis and release of cytokines such as IL-2, IL-12 and IFN-γ by DCs.
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Colorectal cancer (CRC) is a complex disease due to the large number of factors that influence its development, including variants in tumor suppressor genes. ⋯ The presence of TSC2 gene c.3915G>A variant suggests a possible protective effect against sporadic CRC in the Mexican population; however, no association was observed with the c.5371G>A variant.
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Fibromyalgia (FM) is a non-degenerative syndrome characterized by generalized, chronic musculoskeletal pain, as well as mood, memory and sleep disorders. ⋯ 30% of FMPs have ANeuA that have not been described before. In future studies, it will be necessary for anti-neural immunoreactivity to be determined in a larger sample and for the role of ANeuAs in the pathophysiology of FM to be established.