Hippokratia
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Case Reports
The importance of minimal residual disease for detection of late relapse in Bprecursor acute lymphoblastic leukemia.
The minimal residual disease (MRD) level in patients with B-precursor acute lymphoblastic leukemia (B-ALL) is the strongest independent predictor of relapse and survival. Assessment of MRD plays a crucial role in the treatment of B-ALL. ⋯ This case illustrates that more extended monitoring for MRD, even by only MFC when other newer sophisticated diagnostics are not available, is essential in detecting early relapse in patients with B-ALL of standard risk. HIPPOKRATIA 2022, 26 (1):38-40.
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Acute appendicitis and cholecystitis during pregnancy are the most common non-obstetrical surgical emergencies and can create severe clinical issues. Surgical treatment tends to be the method physicians recommend due to its tolerability and safety. During pregnancy, surgical intervention should minimize fetal risk without compromising the mother's health, although a favorable outcome for pregnant women is heavily dependent on accurate, early diagnosis and prompt intervention. Furthermore, the physicians should remain informed on the differences in current techniques to optimize the outcome of the operation. ⋯ Our meta-analysis and data suggest that laparoscopic appendectomy is a safer option for treatment. There is a reduced risk of fetal demise and preterm delivery for pregnant women. HIPPOKRATIA 2022, 26 (1):1-6.
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As hand osteoarthritis (HOA) is a highly prevalent disease, the purpose of the present study was to examine the relationship between structural damage of the hand in HOA patients and assess its impact on their hand function, pain, and satisfaction. ⋯ The study findings reveal that respondents with more severe structural damage experienced more significant pain, reported greater functional and work-related limitations, and were more dissatisfied with the function and appearance of their hands. HIPPOKRATIA 2022, 26 (1):7-12.