Hippokratia
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Detecting liver dysfunction/failure in the intensive care unit poses a challenge as individuals afflicted with these conditions often appear symptom-free, thereby complicating early diagnoses and contributing to unfavorable patient outcomes. The objective of this endeavor was to improve the chances of early diagnosis of liver dysfunction/failure by creating a predictive model for the critical care setting. This model has been designed to produce an index that reflects the probability of severe liver dysfunction/failure for patients in intensive care units, utilizing machine learning techniques. ⋯ Our machine learning approach facilitates early and timely intervention in the hepatic function of critically ill patients by their healthcare providers to prevent or minimize associated morbidity and mortality. HIPPOKRATIA 2024, 28 (1):1-10.
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Background: Patient-reported outcome measures (PROMs) assess how individuals perceive the disease and its impact on quality of life, representing an important complement to the metabolic evaluation in type 1 diabetes mellitus (T1DM). This study aimed to assess the PROMs and their association with metabolic control. ⋯ Including PROMs alongside detailed metabolic evaluation allows for individualized decision-making and active patient participation in diabetes management. These results underscore the importance of preventing depression, promoting well-being, and enhancing diabetes psychological adjustment in these patients, aiming to improve their quality of life. HIPPOKRATIA 2024, 28 (1):17-21.
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The ever-increasing sport level makes every single detail of the athlete's cardiorespiratory profile count, and therefore, it is deemed crucial to clarify how the anterior cruciate ligament (ACL) reconstruction (ACLR) affects the energy economy of an athlete compared to the ACL-deficient and healthy subjects. The purpose of this review was to systematically analyze the studies investigating the correlation between the energy-oxygen cost in patients following ACLR in unreconstructed and intact ACLs. ⋯ ACL insufficiency affects substantially the metabolic energy costs, resulting in increased energy expenditure. According to current literature, ACLR can help to partially reverse this condition, as significant improvements and a more efficient, energy-wise, locomotion are expected. However, further research is necessary to clarify if ACLR can completely normalize energy expenditure again. HIPPOKRATIA 2023, 27 (4):119-125.