Hippokratia
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The role of the sternum, if any, in the aetiopathogenesis of adolescent idiopathic scoliosis (AIS) remains unexplored. We evaluated morphological features of the sternum for the first time in individuals with AIS. ⋯ These are preliminary data demonstrating for the first-time morphological differences of the sternum, between AIS and age-matched non-scoliotic individuals. The sternum of adolescents with AIS was more inclined than non-scoliotic controls that could raise the hypothesis of sternum involvement in AIS pathogenesis. HIPPOKRATIA 2018, 22(4): 173-177.
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Hepatic cirrhosis caused by hepatic steatosis and hepatitis is irreversible. Early and non-invasive diagnosis of these diffuse hepatopathies calls for possible imaging markers. The purpose of this study was to explore the changes in global hepatic glucose metabolism following hepatic steatosis, hepatitis, or cirrhosis on 18F-2-fluoro-2-D-deoxyglucose-positron emission tomography (18F-FDG PET)/computed tomography (CT). ⋯ SUVmean, together with GHG, can reflect hepatic functional capacity, which can be regarded as potential imaging markers in assessing diffuse hepatopathies. HIPPOKRATIA 2018, 22(4): 162-166.
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Therapeutic apheresis (TA) as primary or adjunctive therapy proved itself in a broad spectrum of diseases. This study aims to present TA practices in a tertiary center with an emphasis on the rate of the utility of TA on the new American Society for Apheresis (ASFA) indications. ⋯ Therapeutic apheresis is a progressively developing, safe, and effective treatment modality with add-on indications. Physicians should keep track of new developments on this modality to implement the appropriate indications into clinical practice. HIPPOKRATIA 2018, 22(4): 167-172.
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Review
The impact of perinatal history in the occurrence of childhood obesity: a litera-ture review.
It is widely accepted, that the increased prevalence of childhood overweight and obesity poses an important public health problem since it increases the risk for early onset of non-communicable diseases with potentially increased health complications during adulthood. Childhood obesity prevention is therefore of primary importance; hence it is mandatory to understand its main causes and identify the mechanisms associated with weight gain. Although its etiology can be partly attributed to genetic and behavioral factors, evidence from existing literature indicates that the perinatal environment may also increase the risk of childhood obesity; the latter, however, has not been thoroughly investigated and discussed. ⋯ Public health professionals should take into account perinatal determinants when estimating a child's risk of overweight and obesity development. HIPPOKRATIA 2018, 22(4): 155-161.