J Postgrad Med
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Randomized Controlled Trial Clinical Trial
Effect of epidural morphine on minimum alveolar concentration of isoflurane in humans.
The anaesthetic potency of volatile anaesthetic agents is measured by the minimum alveolar concentration (MAC) required to suppress response in 50% of subjects. We studied the effect of epidural morphine on MAC of isoflurane in humans. ⋯ Epidural administration of 3 mg morphine in 10 ml saline decreased the MAC of isoflurane.
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Letter Case Reports
Transient segmental spinal myoclonus due to spinal anaesthesia with bupivacaine.
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Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of intravenous ketoprofen versus pethidine on peri-operative analgesia and post-operative nausea and vomiting in paediatric vitreoretinal surgery.
To compare the efficacy of ketoprofen and pethidine for peri-operative analgesia and post-operative nausea and vomiting in children undergoing vitreoretinal surgery and surgery for retinal detachment. ⋯ Ketoprofen is a satisfactory alternative analgesic to pethidine for vitreoretinal surgery and results in a lower incidence of postoperative nausea and vomiting.
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Review
Role of left cardiac sympathetic denervation in the management of congenital long QT syndrome.
Congenital long QT syndrome (LQTS) is a rare but life-threatening disorder affecting cardiac electrophysiology. It occurs due to mutation in genes encoding for the ion channels in ventricular cell membrane. Syncopal attacks and cardiac arrest are the main symptoms of the disease. ⋯ The recent advent of minimally invasive thoracoscopic sympathectomy may improve the acceptance of LCSD by physicians and patients in the future. The primary objective of this article was to review the current evidence of the clinical efficacy and safety of LCSD in the management of LQTS. The review was based on Medline search of articles published between 1966 and 2002.