J Postgrad Med
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Aleatory uncertainties are generated by intrinsic factors such as studying a sample rather than the whole population and the source of epistemic uncertainties is extraneous such as limitations of knowledge. These uncertainties inflict all the findings in empirical medical research, but they are rarely appreciated. ⋯ We conclude that aleatory and epistemic uncertainties should get due consideration while drawing conclusions and before the results are put into practice. Methods to reduce their impact on results are also presented.
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Observational Study
The predictors of outcome and progression of pediatric sepsis and septic shock: A prospective observational study from western India.
There is a paucity of studies on the progression and outcome of Systemic Inflammatory Response Syndrome (SIRS) with its determinants. ⋯ SIRS can progress to septic shock if not identified early. The predictors of mortality were positive blood cultures, multiorgan dysfunction, late hospital admissions, severe acute malnutrition, and requirement of supportive care. The predictors of progression to septic shock were abnormal leukocyte count, culture positivity, and severe acute malnutrition.
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Fixed drug eruption is one of the most common forms of cutaneous adverse drug reactions. Analgesics and antibiotics are the most common drugs causing fixed drug eruption. Here, we report a case of multiple widespread fixed drug eruption caused by rabeprazole.
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Hypertension is one of the leading causes of premature deaths worldwide. Drivers have an additional risk of hypertension when compared to the general population because of the nature of their profession. Hence, the current review was done to estimate the global burden of hypertension among professional drivers. ⋯ More than one-third of drivers have hypertension globally which is in excess of the general population. Hence, more focus needs to be given for allocating resources and developing workplace interventions for prevention and control of hypertension.
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[This corrects the article DOI: 10.4103/0022-3859.138816].