J Res Med Sci
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Since December 2019, the world is struggling with an outbreak of coronavirus disease-2019 (COVID-19) infection mostly represented as an acute respiratory distress syndrome and has turned into the most critical health issue worldwide. Limited information is available about the association between dynamic changes in the naso/oropharyngeal viral shedding in infected patients and biomarkers, aiming to be assessed in the current study. ⋯ Based on the current study's findings, the duration of SARS-CoV-2 RNA shedding was directly correlated with the required time for LDH and CRP return to normal levels. Therefore, these factors can be considered the determinants for patients' discharge, isolation, and return to social activities; however, further investigations are required to generalize the outcomes.
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The present study was performed to investigate and compare renal functions of single-kidney patients after 12 h of percutaneous nephrolithotomy (PCNL) surgery through assessing major markers of renal function with focus on serum level of cystatin that performs a consistent accuracy in various conditions. ⋯ Due to significant improvement in all markers of renal after PCNL, this procedure can be considered a potentially effective and safe approach for treating large stone in single-kidney patients.
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The adaptive immune system plays a role in the pathogenesis of idiopathic pulmonary fibrosis (IPF) has been reported previously. However, the association between airway and circulating autoantibodies (AAbs) levels is unclear. The aim of this study is to investigate the link between the AAb levels in airway and circulation in stable patients with IPF. ⋯ Comparing to Se-AAbs, Sp-AAbs are more associated with clinical parameters in the patients with IPF. In order to better understand the role of autoimmunity in the pathogenesis of IPF, detection of Sp-AAbs for local autoimmune responses may be a good choice.
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Paddy cultivation of rice requires substantial physical strength, perseverance and manual labor. During the manual harvesting of paddy rice in Iran, laborers are exposed to several work-related physical risks. Paddy cultivation has been reported as one of the most important causes of nonfatal occupational injuries and accidents among farmers. With the aim of identifying which parts of the musculoskeletal structure are mostly affected as a result of working on paddy rice fields, the present study aimed to investigate the potential risk factors for musculoskeletal problems in paddy field workers in Mazandaran Province, Iran. ⋯ Disorders in certain body regions could be explained by specific individual and work-related factors. While the prevalence of work-related injury was high, mostly due to ignorance and disregard for personal convenience of the workers, the findings call for improvements in mechanization and division of labor time and force. Another highlight is that social worth is not given sufficiently to the health of paddy field workers. These should be worked on in future research to find ways of allocating machinery and worth to the workers.
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Suitable mechanical ventilation strategies can reduce the incidence and severity of ventilator-associated lung injury in patients with acute respiratory distress syndrome (ARDS). In this study, the effects of adaptive support ventilation (ASV) and synchronized intermittent mandatory ventilation (SIMV) on respiratory parameters and arterial blood gases (ABGs) parameters were compared in ARDS patients. ⋯ By reducing PIP and improving oxygenation and ABG parameters, ASV mode may be a safe and feasible mode during mechanical ventilation in patients with ARDS.