J Res Med Sci
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The study aimed to detect the association between insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and interleukin-6 (IL-6) polymorphisms among type 2 diabetes mellitus (T2DM). ⋯ The current study indicated that IGF2BP2 rs4402960 and IL-6 rs1800795 polymorphism were highly significantly associated with the increased risk of obese T2DM among the Saudi Arabian population and presented a genetic model to screen the high-risk individuals with further validations.
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Few studies explore the patient heterogeneity, trajectory development, and factors influencing the functional recovery of the postacute care cerebrovascular disease (PAC-CVD) program. The objective of the study was to analyze the group-based trajectory and different functional improvement for patients with acute stroke participating in the PAC-CVD program. ⋯ Identifying initial functional groups can guide medical professionals to target patients for PAC service use. PAC-CVD high-intensity rehabilitation significantly enhances acute stroke patients' functional recovery, though effectiveness varies over time. These factors highlight the need for further development of rehabilitation programs to boost patient independence.
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Diabetic retinopathy (DR) is one of the complications of diabetes. This study was conducted to investigate the effect of curcumin-piperine on laboratory factors and macular vascular in DR. ⋯ Curcumin-piperine is effective in improving oxidative stress and reducing creatinine in DR. Further trials are necessary to confirm these promising findings.
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The diagnosis of chronic rhinosinusitis (CRS) is a crucial and challenging entity in bone marrow transplantation candidates. We aimed to evaluate the diagnostic accuracy of the Sino-Nasal Outcome Test (SNOT-22) and Lund-Kennedy endoscopic score for the diagnosis of CRS in bone marrow transplantation candidates. ⋯ The Lund-Kennedy endoscopy score could diagnose CRS in bone marrow transplantation candidates with satisfactory accuracy, whereas SNOT-22 lacks enough accuracy to be employed as an independent sino-nasal assessment modality in these patients.