J Res Med Sci
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The objective of the present study was to determine the association between chemotherapy and infectious complications in patients diagnosed with Hematologic malignancies (HMs). ⋯ Regarding the chemotherapy regimen, the highest incidences of infectious complications were observed for growth factors and cytarabine.
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This study aimed to use social network analysis (SNA) indicators and clique analysis to investigate collaboration between different departments and research centers in Journal of Research in Medical Sciences (JRMS) in 2012-2016. ⋯ Given the importance and position of scientific collaboration in medical research and its effect on other performance indicators such as efficiency, effectiveness, and number of citations, it is necessary for policy-makers to propose new strategies for improving scientific collaboration.
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Spleen is the most common viscera that may be hurt in blunt abdominal trauma. Operative or nonoperative management of splenic injury is a dilemma. The American Association for the Surgery of Trauma (AAST) is the most common grading system which has been used for the management of blunt splenic injuries. The new recommended grading system assesses other aspects of splenic injury such as contrast extravasation, pseudoaneurysm, arteriovenous fistula, and severity of hemoperitoneum, as well. The aim of this study is to compare and prioritize the cutoff of AAST grading system with the new recommended one. ⋯ In contrast to the previous studies, the new splenic injury grading method was not superior to AAST. Further studies with larger populations are recommended.
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Depression is a common medical condition with a high prevalence leading to emotional abnormality. Despite some drawbacks, depression currently diagnosed using a combination of patient interviews and self-report questionnaires. Recently, there is emerging emphasis to establish biomarkers to diagnosis and clinical management of depression. This case-control study was designed to develop microRNA (miRNA)-based serum biomarker for depression. ⋯ Our findings showed that these miRNA can be used as a biomarker of depression diagnosis. MiR-135a and miR-1202 exhibited better sensitivity and specificity, respectively.
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Diabetes is associated with oxidative stress and considered as a major risk factor for cardiac disease. We attempted to investigate the role of oral antidiabetic (OAD) agents gliclazide and metformin in lowering the lipid peroxidation and managing the risk for cardiovascular (CV) complications in diabetic patients in comparison with nondiabetic healthy individuals. ⋯ Our data confirmed that treatment with gliclazide and metformin significantly reduced the lipid peroxidation accompanied with attenuated levels of serum TGs and cholesterol and suggested that oral hypoglycemic agents have great impact to reduce the oxidative stress and increase the antioxidant status in diabetes.