Presse Med
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A NON-ENVELOPED VIRUS: The hepatitis E virus is non-enveloped and measures approximately 32-34 nm in diameter. Its genome is a single stranded 7.5 kb RNA with three open-reading frames designated ORFI, 2 and 3. There is only one genotype, but several strains have been identified, with relatively high homology.
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Review Practice Guideline Guideline
[Autoimmune thrombopenic purpura. Clinical practices during diagnosis. A French survey and recommendations. French College of Hemotologists Evaluation Commission].
THE SURVEY: To better ascertain diagnostic and treatment strategies used by physicians for idiopathic thrombocytopenic purpura, a questionnaire was addressed to 298 French hematologists and pediatricians. One hundred and ten responses were analyzed.
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TOP PRIORITY: Preventing hemorrhage is the number one priority in the treatment of idiopathic thrombocytopenic purpura. There are three main treatments: corticosteroids, intravenous immunoglobulins and splenectomy.
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A LOGICAL HYPOTHESIS: Recent publications raise the question of an association between Chlamydia pneumoniae and asthma. There has been no formal proof justifying routine search for C.pneumoniae in patients with uncontrolled asthma nor for systematic treatment with an antibiotic.
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Review
[Action of cytokines IL-12 and IL-4 on T helper cells. Cellular immunity or humoral immunity?].
TWO SUBSETS OF T-HELPER CELLS: T-helpers are divided into two subpopulations called Th1 and Th2 depending on the pattern of cytokines they produce. These mutually antagonist subpopulations exert different functions: Th1 cells control cellular immunity whereas Th2 cells control humoral immunity.