Presse Med
-
Multiple osteosarcoma is a rare tumour which usually has a poor prognosis. We report the case of a 14-year old girl who developed successively, at 2 1/2 years' interval, one osteosarcoma of the right radius bone, then one of the left radius bone. ⋯ At present, 5 years after the first treatment, she is in good health. This case is remarkable on several scores: chemotherapy was feasible and well tolerated, the multiple osteosarcoma had a favourable outcome, and conservative surgery of both radius bones gave satisfactory functional results.
-
Epidermoid carcinoma of the penis is a rare type of cancer. Treatment of the primary lesion consists of amputation, although curietherapy can be effective in some cases as a conservative treatment. The prognosis is determined by the presence of absence of lymph node invasion, but the therapeutic strategy to be used when invaded lymph nodes are present remains controversial. Lymph node dissection is the only effective treatment of metastatic adenopathy, but its high morbidity rate limits its indications.
-
The authors report the case of a 57-year old woman who was susceptible to malignant hyperthermia (MH) and also had central core disease (CCD) of muscle. The latter was asymptomatic and was discovered when muscle biopsy was performed for in vitro tests of susceptibility to malignant hyperthermia. This case was compared with the 117 cases of CCD and 33 cases of CCD associated with MH published in the literature. ⋯ Susceptibility to MH is a functional abnormality of unknown mechanism. CCD is a disease of muscle fibre structure. One may hope that molecular studies and genetic probes will show whether or not these two diseases are transmitted by genes that are similar but distinct and independent.