Srp Ark Celok Lek
-
Radiotherapy combined with platinum compounds in widely used despite unclear biological basis and mechanism of their potentiation. We started a prospective nonrandom study on January 1, 1991 with the aim to ameliorate local tumour control and possibility of curative treatment, and treatment of toxicyty.
-
Incidence of postoperative pulmonary complications (6-76%) depends on diagnostic criteria. Seventy four paediatric surgical patients were analysed during one-year period. In the first group (with complications) pneumonia was the most frequent complication (86.95%) in 65.21% of newborns. ⋯ Mortality rate was high in the first group, where more than a half of children were newborns. In conclusion, pulmonary complications had unfavourably influence on the mortality rate and morbidity, particularly in newborn infants. This was the reason for a prolonged hospitalisation in the paediatric intensive care unit.
-
The most frequent complication of lumbar puncture is headache. It is due to lowered intracranial tension produced by a continued leakage of cerebrospinal fluid (CSF) through the dural puncture site. Epidural injection of autologous blood has been frequently reported as highly effective in the treatment of lumbar-puncture-induced headache, with success rates of 73 to 98%. ⋯ We have not observed any side-effects in our patients. Our results are in harmony with the published high efficiencies of autologous epidural blood patch in the treatment of postlumbar-puncture headache. We recommend the injection of 5 ml of autologous blood in the epidural space in all patients with severe lumbar-puncture-induced headache, resistant to conservative therapy, lasting more than 24-48 hours.
-
Glycolisated hemoglobin (HBA1c), fructosamine, glucose, albumin and total proteins were estimated 40 healthy pregnant women and 90 pregnant women with diabetes mellitus. Fructosamine was estimated by NBT method with "Fructosamine test" commercially available kit on Technicom automatic analyser RA-1000. ⋯ HBA1c was assayed by Bio-Rad test, while albumin and total proteins by Beckmman tests. We found best correlation between fructosamine and HBA1c at pregnant women who were on dietary therapy worst at pregnancy women on insulin therapy.
-
During a nine-month period we have treated 46 patients with status epilepticus with intravenous application of diazepam or midazolam. The initial doze od diazepam was 10 mg (rate: 2-5 mg/min) and of midazolam 15 mg (rate: 5 mg/min). Diazepam was effective in 26 and ineffective in 15 patients. ⋯ All patients with apnea or respiratory depression received higher doses of both drugs at the higher rates than the others. We conclude that the efficacy of the therapy is moderate while the frequency of serious complications is high. In status epilepticus, where the life of patient is in danger, drugs with such activity are of limited value.