Srp Ark Celok Lek
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Meningiomas are slow growing, extra-axial lesions, and can be neurologically silent for a long time and present only with depression. ⋯ Total resection of convexity meningioma and decompression of the brain tissue in the region of limbic pathways that are involved, may contribute to a complete remission of depression symptoms. This case also illustrates the need for a prompt neuroimaging of the brain when patients present any atypical psychiatric symptoms, with late onset (> 50 years old) of the first depressive episode or fast changes of the mental state.
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Ultrastructural changes in corneas of patients with diabetes mellitus have been previously described. ⋯ CDR of diabetic patients was higher compared to healthy subjects. The highest mean value of CDR was registered in the PDR group, followed by the NPDR and the NDR groups.
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Intracranial chondroma is a very rare, slow growing, benign cartilaginous tumor that arises usually from the base of the scull. Chondroma located at the falx is extremely rare. According to our best knowledge 15 cases of falx chondromas have been reported in the literature. ⋯ The long-term prognosis is good after a total excision of the tumor. Awareness of this rare pathology in the differential diagnosis of falx mass could facilitate the diagnosis.
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The aim of this paper was to present the role of human papillomavirus (HPV) in cervical carcinogenesis from several aspects. By explaining the HPV virus lifecycle and structure, its effect on cervical cell cycle and subversion of immune response can be better understood. Early E region of the viral genome encodes proteins that are directly involved in carcinogenesis. ⋯ Presentation through Langerhans cells (LC) is weak, because the number of these cells is low due to the effect of HPV. E7 HPV reduces the expression of E-cadherin, which is responsible for LC adhesion to HPV-transformed keratinocytes. Based on these considerations, it may be concluded that the process of cervical carcinogenesis includes viral, genetic, cellular, molecular-biological, endocrine, exocrine and immunological factors.
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Case Reports
Reconstruction of full thickness abdominal wall defect following tumor resection: a case report.
Reconstruction of a full thickness abdominal wall defect is a demanding procedure for general and also for plastic surgeons, requiring vigorous planning and reconstruction of three layers. ⋯ Omenthoplasty, abdominal wall reconstruction in combination with free fascia lata graft and skin grafts can be one of good options for the reconstruction of full thickness abdominal wall defects.