Terapevt Arkh
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Paraprotein is a laboratory biomarker of plasma cell tumors and other lymphoproliferative diseases. Its determination is necessary for diagnosing, monitoring and assessment of therapy effectiveness. ⋯ The main sources of errors and artifacts during these studies are considered. Also the difficulties in the diagnosis and interpretation of the results of serum and urine tests are highlighted.
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To assess the relationship of psychoemotional changes with obesity in young men, depending on the age of manifestation of the disease and against the background of the program of weight loss. ⋯ In the group of patients with manifestation of obesity since puberty, the frequency of depressive disorders was higher than in the group of young men with onset of obesity since childhood.
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Randomized Controlled Trial
[Evaluation of the efficacy and safety of a complex antiviral drug based on antibodies in the treatment of adult patients with acute respiratory viral infection].
To evaluate the efficacy and safety of Raphamin, containing technologically processed affinity-purified antibodies to interferon , CD4 receptor, 1 domain of the major histocompatibility complex class II and 2 microglobulin major histocompatibility complex class I in the treatment of acute respiratory viral infection (ARVI), including influenza, in adults. ⋯ Raphamin promotes significant decrease, practically by a day, the duration of ARVI, including influenza.
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Multicenter Study
[Multicenter study of gastroesophageal reflux disease symptoms prevalence in outpatients in Russia].
Recently, there has been an increase in the prevalence of gastroesophageal reflux disease (GERD) in Northern Europe, North America and East Asia. However data on GERD prevalence in Russian population are very limited. ⋯ The results of this study indicate a high prevalence of GERD among residents of Russian cities applying for primary health care (34.2%). In comparison with previous studies, an increase in the proportion of GERD patients taking proton pump inhibitors was noted; in most cases the regimen of their intake was in accordance with the recommendations.
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A low hemoglobin level in older adults impairs cognitive ability and functional status and associates with risk of falls and fractures, sarcopenia, malnutrition, depression, frailty, and decreased autonomy. Epidemiological data on the anemia prevalence in the geriatric population in our country is not available. ⋯ EVKALIPT study obtained domestic data on the prevalence of anemia in older patients and examined its associations with other GS.