Terapevt Arkh
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Review Case Reports Comparative Study
[The characteristics of iron metabolism in B12-deficient anemias (an evaluation of the functional status of megaloblastic erythropoiesis)].
The review of the literature data and the evidence obtained on 85 own patients with B12-deficiency anemia concerning iron metabolism underlie 3 variants proposed by the authors: pronounced manifestations of secondary sideroachresia before B12 therapy, utilization iron deficiency upon B12 introduction, dimorphic anemia (development of megaloblastic erythropoiesis in prior iron deficiency). The causes of megaloblastic erythropoiesis incompetence (slow rate, hemolytic component, secondary sideroachresia) are discussed.
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Comparative Study
[A comparative study of the efficacy of Tilade and intal in atopic bronchial asthma].
The authors compared the responses of patients with atopic asthma to two cromolyn drugs of different generations, tilade and intal. As shown by clinical, allergological and immunological findings, tilade (sodium nedocromil) compared to intal is more active against atopic bronchial asthma complicated by obstructive bronchitis. It can more efficiently reduce specific and nonspecific bronchial hyperreactivity, is more potent against inflammation. Due to tilade, the need in glucocorticoid inhalation lowered, it became possible to induce a prolonged remission.