Terapevt Arkh
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Comparative Study
[Activity of renin-angiotensin-aldosterone system (RAAS) and vasopressin level in patients with primary pulmonary hypertension].
Assessment of RAAS and vasopressin in patients with primary pulmonary hypertension (PPH). ⋯ PPH patients display a noticeable activation of RAAS and VP. This activation seems to be secondary as the changes increase with elevation of the pressure in the pulmonary artery and aggravation of circulatory insufficiency. Plasma renin activity determines the degree of RAAS activation as a whole. The discovered activation of RAAS in PPH gives grounds for doubts in the validity of using ACE inhibitors in the treatment of PPH.
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Comparative Study
[Complex assessment of inhacort effectiveness in bronchial asthma].
To investigate efficiency of inhacort in long-term (6 months to 2 years) treatment of bronchial asthma (BA). ⋯ Inhacort in a dose 1 mg controls BA. 73% of the patients treated outpatiently had no need in hospitalization.
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Comparative Study
[Significance of antibodies to herpesviridae viruses detectable in rheumatic diseases].
To assay antibodies to cytomegalovirus (CMV), herpes simplex virus type 1 and 2 (HSV-1, HSV-2) and Epstein-Barr virus (EBV) in rheumatic patients and to clarify clinical correlations. ⋯ In differential diagnosis of rheumatic diseases it is necessary to consider possibility of CMV and EBV infections. If these are detected, antiviral measures should be taken.
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Comparative Study
[HLA-antigens and some pathogenetic aspects of reactive arthritis].
Investigation of associations of reactive arthritis (ReA) with histocompatibility antigens class I and II and determination of new approaches to assessment of association ReA with antigen HLA B27. ⋯ In HLA-B27-subjects optimal conditions exist for generalization of obligate parasites and favorable for production of facultative ones. The degree of association of ReA with HLA B27 antigens is dependent on adaptive features of microorganisms appearing in the process of evolution--obligaty and facultativeness of their internal parasitivity.