Terapevt Arkh
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Comparative Study
[The effect of socioeconomic status on the prevalence of biliary tract diseases in the Evens and Evenki].
An epidemiological survey demonstrated that biliary disease detection in aborigines of the Far North is more frequent in subjects with nontraditional way of life. Chief biliary disease factors different in importance for Evens and Evenks are as follows: prior viral hepatitis, obesity, alcohol abuse. Incidence rate for different biliary diseases is not uniform in Far North native population. This may be explained by specificity of biliary functions.
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Twenty-one patients with hemorrhagic vasculitis (HV) were examined for HBsAg, nine for HBeAg, anti-HBe, anti-HBc, anti-HBs. HBV markers were identified in 6 out of 21 patients (29.6%): HBsAg in 5 cases (one of them also anti-HBc and anti-HBe), anti-HBs in 1 case. The history of HV ranged from 4 months to 8 years. ⋯ It was somewhat elevated in 1 of the examinees due to cytostatic treatment in parallel growing of HBsAg titer. Cryoglobulins occurred in 3 out of 6 cases. Renal biopsy from 3 HBV markers carriers identified mesangioproliferative glomerulonephritis in all of them.
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Comparative Study
[Adaptive and non-adaptive reactions of central hemodynamics to conditions of heat discomfort].
Chest rheography was used to study central hemodynamics in 134 healthy males aged 18-28 in comfortable weather conditions and discomfortable ones, that is at equivalent-effective temperature 17-24 degrees C and above 27-30 degrees C, respectively. In trained subjects from native and non-native population under comfortable weather conditions heart rate (HR) proved to be significantly reduced as compared to untrained subjects (57.6 +/- 1.1 and 56.2 +/- 1.2 against 73.9 +/- 1.7 and 70.4 +/- 0.9), whereas stroke volume in trained males was significantly larger (by 14.2 and 14.0%, respectively). Minute blood volume (MBV), cardiac and stroke indices, systolic and diastolic pressure showed no significant differences. ⋯ This was secured by stroke volume elevation by 14.3, 10.7 and 11.2%, respectively (p < 0.05), in non-natives by acceleration of heart rate by 11.2%. A trend to lowering of arterial pressure was more marked in untrained examinees of both populations. It is evident that in conditions of arid zone heat discomfort trained subjects from both native and non-native populations exhibited adequate hemodynamic responses, whereas strain was observed in circulatory system functioning when it adapted to heat discomfort in untrained non-natives.
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Twenty-three patients with Behçet's disease (BD) meeting the criteria of the international group for classification and diagnosis of BD (17 men and 6 women) were typed for HLA antigens class 1. The patients group was multinational, of them 19 were Caucasoids and 4 Mongoloids. It was shown that HLA B5 in Caucasoids occurred more frequently vs normal controls (73.7% and 15.5%, respectively). ⋯ In antigen group B5 + B35 the relative risk and association power grew still higher. The B5 positive group statistically more frequently had superficial thrombophlebitis and less frequently gastrointestinal involvement. It is concluded that class 1 HLA antigens, B5 in particular, are closely associated with BD in CIS countries.