Terapevt Arkh
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Change in the stroke volume in ventricular extrasystoles was studied in 27 patients. In patients with cardiac insufficiency a decrease in the extrasystolic stroke volume was more noticeable than in patients without cardiac insufficiency. "Hemodynamic debts" for extrasystolic and postextrasystolic contractions in patients with the presence and absence of cardiac insufficiency were undistinguished. In interpolated extrasystoles "hemodynamic debts" were less than in non-interpolated.
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Hemoperfusion was applied to the treatment of 20 patients with fulminant meningococcemia complicated by the infectious-toxic shock, stage III, and the polyorgan insufficiency syndrome. Ten patients recovered while the remaining 10 died mainly because of irreversible lesions of the vitally important organs: kidneys, adrenals, heart and brain. ⋯ Hemoperfusion was instituted immediately after elimination of arterial hypotension. The use of hemoperfusion promoted the abatement of systemic toxicosis and neurotoxicosis, the recovery and stabilization of the hemodynamics, improvement of rheological properties of the blood, the recovery of effective tissue perfusion, the lowering of specific antigenemia and blood toxicity, and elimination of the pathological protein complexes from the circulating blood.
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Comparative Study
[Mitral valve prolapse in residents of different altitudes in the Tien Shan and Pamirs].
A study was made of mitral valve prolapse (MVP) in 1197 Kirghiz mountain-dwellers aged 16 to 22 living constantly at different altitudes of the Tien Shan and the Pamirs. MVP was detected in 24 persons (10.9%) living at an altitude of 3600-4200 m above sea level using the method of echocardiography. ⋯ It was shown that MVP in inhabitants at high altitudes was accompanied by more pronounced subjective symptomatology, frequently with various rhythm disorders, hypertrophy of the right ventricle and interventricular septum. It was found appropriate that mountain-dwellers with MVP should be attributed to a risk group with adequate prophylactic medical examination.
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A study was made of the presence of antinuclear antibodies to Ro, La, nDNA, RNP and Sm in 18 patients with Sjögren's disease (SD) and in 13 patients with Sjögren's syndrome (SS). Anti-Ro and/or anti-La were revealed in 12 SD patients (67%) and in 3 SS patients (23%, P less than 0.05) only. ⋯ Anti-Ro only were detected in 44% of the SD patients only and in none of the SS patients. Higher values of ESR, RF and CIC were revealed in the SD patients with anti-La and especially anti-Ro.