Turk J Med Sci
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To determine the knowledge about and acceptance level of monkeypox vaccine in men who have sex with men (MSM). ⋯ Despite the low level of knowledge about monkeypox, the majority of the participants reported that they believed in the vaccine's efficacy. Those who were HIV-positive were particularly more concerned about monkeypox and were more willing to protect themselves compared to those who were HIV-negative.
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Hepatocellular carcinoma (HCC) ranks among the most prevalent malignancies worldwide and the third leading cause of cancer-related death. The TRIM (tripartite motif-containing) protein family members had been reported to be involved in carcinogenesis and tumor progression. Here we aimed to explore the expression profile of TRIM6 in HCC and investigate its clinical significance as well as underlying mechanisms. ⋯ TRIM6 can serve as a novel prognostic factor for HCC, which functions by multiple signaling pathways.
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Comparative Study
Comparison of the effect of postweaning social isolation, enriched environment, and exercise training on learning and memory functions in rats.
To assess the effects of postweaning social isolation, an enriched environment, and exercise training on learning and memory functions in rats, as well as their relation with the brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) concentrations in the hippocampus. ⋯ Postweaning social isolation may increase thigmotaxis behaviors. Postweaning social isolation, enriched environment, and exercise training did not affect the spatial learning, memory function, hippocampal BDNF or NGF levels in female rats.
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This study investigated the possible degeneration in cochlear morphology induced by preeclampsia (PE) and the therapeutic/preventive effect of vitamin D (Vit D) and magnesium sulfate (MgSO4) used separately and together on feto-maternal outcomes. ⋯ The administration of Vit D and MgSO4 during pregnancy has beneficial effects on PE pathology and may play a significant role in preventing PE-related complications, including cochlear degeneration.
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To investigate the effects of acetylsalicylic acid (ASA) and the use of ultrasound elastography on testicular torsion. ⋯ ASA treatment for testicular torsion was shown to be ineffective. Elastography can be a complementary method to Doppler ultrasonography in the diagnosis of testicular torsion and can guide surgeons in their approach to surgery.