Turk J Med Sci
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Increasing international migration poses unique challenges, especially regarding health outcomes and behaviors such as substance use. This study aims to identify risk factors influencing substance use among Turkish-origin immigrants in Germany. ⋯ Substance use among Turkish-origin immigrants in Germany is influenced by generational status, with younger and third-generation individuals being at higher risk. Additionally, tobacco and alcohol use are strong predictors of substance use, highlighting the need for targeted interventions, especially for young migrants.
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Observational Study
Relationships between stenosis severity, functional limitation, pain, and quality of life in patients with cervical spondylotic radiculopathy.
This study aimed to examine the relationships between severity of stenosis, pain, functional limitation, disability, and quality of life in patients with cervical spondylotic radiculopathy. ⋯ There are direct relationships between cervical spondylotic radiculopathy and neck and arm pain, numbness, disability, and quality of life. Additionally, an increase in the severity of cervical stenosis is associated with an increase in pain and disability.
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This study was conducted to evaluate the results of autism spectrum disorder (ASD) screenings conducted in a region of İstanbul between 2018 and 2023. ⋯ Autism spectrum disorder is a developmental disorder whose prevalence is increasing globally and for which early diagnosis is important. To recognize this disease, it is necessary to increase screening and raise awareness among families. This study will also shed light on future studies on this subject.
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Y2O3-Al2O3-SiO2 (YAS) glass microspheres are currently used in radioembolization treatment. However, abscess formation can occur following this treatment. This study aims to endow YAS glass microspheres with antibacterial properties to address the abscesses forming in patients after radioembolization treatment. ⋯ The antibacterial agent-doped YAS glass microspheres show promise in combating infections that occur following radioembolization treatment.
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Misfolded proteins are eliminated by a process known as endoplasmic reticulum-associated protein degradation (ERAD). ERAD has an impact on a variety of illnesses, such as diabetes, cystic fibrosis, cancer, and neurological conditions. As one of the many proteins involved in ERAD, this study is focused on p97/valosin-containing protein (VCP) and small VCP-interacting protein (SVIP). The existence and function of SVIP and p97/VCP in various types of pancreatic cancer have not yet been investigated. The study's objectives are to examine the expressions of SVIP and p97/VCP in two pancreatic cancer types and to show whether these proteins aid in the invasion and migration of pancreatic cancer cells. ⋯ Overall, the findings show the differential expression and function of p97/VCP and SVIP in pancreas ductal adenocarcinoma cells. The potential of the pancreatic cancer cells to migrate and invade altered when the two cell lines were transfected with p97/VCPsi and SVIPsi.