Turk J Med Sci
-
Filaggrin is a protein complex involved in epidermal differentiation and skin barrier formation. Mutations of the filaggrin gene (FLG) are associated with allergen sensitization and allergic diseases like atopic dermatitis (AD), allergic rhinitis, food allergy (FA), and asthma. The aim of the study is to reveal the frequency of change in the FLG gene and determine the association between FLG loss-of-function (LOF) mutations and FA and/or AD in Turkish children. ⋯ Although R501X, 2282del4, R2447X, and S3247X mutations are very common in European populations, we found that FLG mutations were infrequent and there is no significant association with food allergy and/or atopic dermatitis in Turkish individuals.
-
Infections caused by Candida species are significantly increasing today, and invasive Candida infections are generally associated with high mortality. Early diagnosis and identification of Candida spp. is important for the determination of antifungal agents that will be used for treatment. The aim of the present study was to provide a better regimen for Candida infections in the future. ⋯ The SYO method was ready-to use, so it appeared to be easier and more efficient for Candida isolates.
-
The aim of this research is to evaluate the relationship between the quality of health and accreditation standards with the Covid-19 process and to reveal the importance of quality and accreditation in health care in the process of combating coronavirus. ⋯ Studies on quality and accreditation in health services are important in terms of being prepared for Covid-19 and similar epidemic and pandemic situations, and to carry out planned and effective management of the process.
-
To evaluate the effect of the long-term use of systemic immunosuppressive drugs on druse formation in patients aged over 50 years. ⋯ Patients who used long-term systemic immunosuppressive drugs had significantly lower hard and soft druse formation rate than age and sex matched control subjects.
-
This study aims to serve as a unique consolidated source in Turkey’s vaccination history and as an example for other countries by objectively revealing the change in mortality and morbidity rates in Turkey following the beginning of vaccination without asserting any claim on the benefits or risks of vaccines. This unbiased research will also help health professionals identify the challenges more easily when they face with the people who hesitate to vaccinate their children. ⋯ The present study demonstrates that many possible diseases and deaths have been prevented through vaccination studies. In this regard, this study demonstrating the importance of vaccination presents that all individuals in the society have a responsibility in this scope when the communicable diseases and wars are taken into consideration. The main responsibility is to ensure that they and their children are vaccinated against communicable diseases that are risky for society’s health.