Turk J Med Sci
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This study aimed to explore the associations of the cholesteryl ester transfer protein (CETP) gene TaqIB and D442G polymorphisms with essential hypertension (EH). ⋯ TaqIB and D442G polymorphisms of the CETP gene did not independently affect the risk of developing EH in the Chinese Mongolian population, while the B2-G haplotype obviously decreased the susceptibility to EH. The B2 allele could alter the blood lipid level and reduce the risk of developing cardiovascular diseases.
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The role of angiogenic factors in gastric cancer is not clear. We aimed to assess the role of vascular endothelial growth factor A (VEGFA), angiopoietin 1 (Ang-1), and placental growth factor (PlGF) in the prognosis of patients with advanced gastric cancer. ⋯ Our results support the use of the new API including VEGFA, Ang-1, and PlGF levels in patients with advanced gastric cancer as a predictor of survival.
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Multicenter Study
Attitudes, wishes, and needs of diabetes patients and their relatives: Turkish data from the DAWN2 study.
The DAWN2 (Diabetes Attitudes, Wishes, and Needs) study was conducted in order to ascertain the wishes, needs, and attitudes of diabetes patients, their relatives, and healthcare professionals. The study was conducted across 17 countries, including Turkey, and its objective was to introduce policies that could successfully meet these requirements. In this article, the needs, wishes, and attitudes of diabetes patients and their relatives in Turkey are compared with those from other countries. ⋯ DAWN2 is the first study of its kind. The problems and shortcomings related to diabetes care and management in Turkey are once again revealed with this study, and important data and opportunities to improve them are presented.
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Maternal, fetal, and neonatal outcomes in parturients with intrahepatic cholestasis of pregnancy (ICP) have been retrospectively documented. We aimed to present pregnancy outcomes of parturients with ICP who underwent delivery. The study was conducted during a 1-year period. ⋯ Parturients with ICP who had normal coagulation parameters despite increased liver enzymes preoperatively underwent cesarean delivery under spinal anesthesia without complication. Although maternal outcomes were generally positive, adverse fetal and neonatal outcomes are more likely to occur, particularly in cases with severe ICP.
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Thirty male BALB/c mice were equally divided into three groups: control, L. acidophilus, and B. bifidum for the assessment of the probiotics' stability in the gut microflora. ⋯ Our results revealed that, unlike B. bifidum, the amount of L. acidophilus remained almost unchanged in the long term, indicating more stability of L. acidophilus than B. bifidum in the gut microflora.