Vojnosanit Pregl
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Randomized Controlled Trial Clinical Trial
[Premedication in peripheral block anesthesia].
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War injuries require specific approach in order to be optimally managed. In case of penetrating or explosive joint injuries, the management should be done with regard of the war surgery doctrine. Besides, it is very hard to prognose the disability degree after the completed treatment. ⋯ For all the reasons cited above, in the last two years we started with the total elbow arthroplasty. In all the patients with implanted elbow endoprosthesis, the improvement in the amplitude of elbow movements was observed. In 20% cases the pain was significantly decreased, and in 80% cases, the elbow became painless.
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Comparative Study
[Comparative study of the analgesic effect of Dikalm and Saridon in headaches of various causes].
Headache, as a syndrome, represents large health and wider socio-economic problem in every community for its massive occurrence and frequent absence of therapeutic response to the administered analgesics. That is why the finding, and later production of the drug that would satisfy the criteria of analgesic, efficacious in the treatment of headache, without the entering in etiology of syndrome are presented as the imperative. In connection with that was set the aim of the investigation: to investigate comparative analgesic efficacity of new preparation--Dikalm compared to analgesic that was for a long time present in our pharmaceutic market--Saridon tablets in the patients with different neurologic diseases, where headache represents the leading symptom of their difficulties. ⋯ The headache intensity, residual headache, adverse effects and the need for repeating were graded by original standardized scales. The results of investigation revealed significantly better analgesic effect of therapeutic combination contained in Dikalm preparation, as for persistent, residual headache, as for the need of repeating the analgesics administration, what was specially pronounced in the group that cross-received both preparations, or in the whole group compared to the therapeutic combination contained in Saridon tablets. It was concluded that Dikalm represented the drug with efficacious analgesic and with minimal adverse effects.
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Inappropriate body response is, besides the infectious agent, responsible for the genesis of sepsis and septic shock. It is non-specific and in cascade of events it can hardly be controlled. The results of immunoglobulins administration compared to the disease course and outcome have been compared and analyzed in 135 patients with sepsis and septic shock. ⋯ Seven (53.85%) patients were cured, and 6 (46.15%) died. In relation to the favorable disease outcome the difference was observed (statistically non-significant) in the group that received immunoglobulins, compared to the group that did not (53.85% vs. 44.45%). The importance of immunoglobulins administration, in sepsis and septic shock should be emphasized.