Neurology
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Comparative Study
Intracranial arterial dolichoectasia and its relation with atherosclerosis and stroke subtype.
To investigate the relationship between intracranial arterial dolichoectasia (IADE) and vascular risk factors, atherosclerosis of the carotid arteries as measured by ultrasound scan, and stroke subtypes. ⋯ IADE was associated with vascular risk factors such as age, male sex, hypertension, previous history of myocardial infarction, and lacunar infarct, but not with carotid atherosclerosis.
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To establish the incidence of muscle weakness in critically ill children. ⋯ Muscle weakness is an infrequent but significant feature of critical illness in children. Transplant recipients seem to be at particular risk.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Gabapentin in the prophylaxis of chronic daily headache: a randomized, placebo-controlled study.
To compare efficacy and safety of gabapentin (GPT) versus placebo for prophylaxis of chronic daily headache (CDH) (headache at least 15 days/month of greater than 4 hours duration over preceding 6 months). ⋯ Gabapentin represents a therapeutic option for chronic daily headache.
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Clinical Trial
Urgent endovascular revascularization for symptomatic intracranial atherosclerotic stenosis.
Endovascular revascularization for intracranial atherosclerotic stenoses is being increasingly performed at major medical centers and has been reported to be technically feasible and safe. The authors report their experience with patients who underwent such a procedure for impending stroke and neurologic instability. ⋯ Endovascular revascularization of intracranial vessels is technically feasible and may be performed successfully. However, periprocedural complication and fatality rates in neurologically unstable patients are high. The results suggest that patient selection, procedure timing, and periprocedural medical management are critical factors to reduce periprocedural morbidity and mortality.
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To use magnetoencephalography to assess possible cortical reorganization in the primary somatosensory cortex (S1) of patients with complex regional pain syndrome (CRPS). ⋯ This study showed reorganization of the S1 cortex contralateral to the CRPS affected side. The reorganization appeared to be linked to complaints of neuropathic pain.