Neurology
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To systematically review outcomes in comatose survivors after cardiac arrest and cardiopulmonary resuscitation (CPR). ⋯ Pupillary light response, corneal reflexes, motor responses to pain, myoclonus status epilepticus, serum neuron-specific enolase, and somatosensory evoked potential studies can reliably assist in accurately predicting poor outcome in comatose patients after cardiopulmonary resuscitation for cardiac arrest.
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Randomized Controlled Trial
A double-blind, controlled study of botulinum toxin A in chronic myofascial pain.
Recent studies have reported a potential analgesic effect of botulinum toxin A (BTXA) in musculoskeletal pain. The present double-blind, randomized, placebo-controlled, parallel clinical trial studied the effect of BTXA on pain from muscle trigger points and on EMG activity at rest and during voluntary contraction. ⋯ The results do not support a specific antinociceptive and analgesic effect of botulinum toxin A.
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Randomized Controlled Trial Comparative Study
Sodium valproate vs phenytoin in status epilepticus: a pilot study.
Sixty-eight patients with convulsive status epilepticus (SE) were randomly assigned to two groups to study the efficacy of sodium valproate (VPA) and phenytoin (PHT). Seizures were aborted in 66% in the VPA group and 42% in the PHT group. ⋯ The side effects in the two groups did not differ. Sodium valproate may be preferred in convulsive SE because of its higher efficacy.
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To assess the influence of the body mass index (BMI) on the prevalence and severity of chronic daily headache (CDH) and its most frequent subtypes, transformed migraine (TM) and chronic tension-type headache (CTTH). ⋯ Chronic daily headache and obesity are associated. Obesity is a stronger risk factor for transformed migraine than for chronic tension-type headache.