Neurology
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Comparative Study
Occurrence of cognitive impairment and dementia in the community: a 9-year-long prospective study.
To determine incidence rates of non-dementia cognitive impairment, to examine the impact of attrition due to death on the observed incidence estimates, and to compare the observed and corrected estimates of non-dementia cognitive impairment with dementia incidence rates. ⋯ Non-dementia cognitive impairment is common and often underestimated in population studies that do not adjust for attrition.
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Gamma knife (GK) radiosurgery has been proposed as an alternative to classic microsurgery in mesial temporal lobe epilepsy (MTLE). Short-term follow-up studies have reported encouraging results, but long-term efficacy is not known. ⋯ Gamma knife radiosurgery is an effective and safe treatment for mesial temporal lobe epilepsy. Results are maintained over time with no additional side effects. Long-term results compare well with those of conventional surgery.
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Editorial Comment
Thinking outside the box: NINDS and the clinical research collaboration.