Neurology
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Comparative Study
Amyloid beta 1-42 and tau in cerebrospinal fluid after severe traumatic brain injury.
To determine whether CSF amyloid beta 1-42 (Abeta-42) and tau have predictive value for prognosis after head injury. ⋯ Abeta-42 and tau may play a potential role in the pathophysiology of TBI. Furthermore, the results of this study suggest that Abeta-42 may be a supportive early predictor for recovery after severe head injury.
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The authors hypothesized that central factors may underlie sensory deficits in patients with nondermatomal somatosensory deficits (NDSD) and that functional brain imaging would reveal altered responses in supraspinal nuclei. ⋯ Diminished perception of innocuous and noxious stimuli is associated with altered activity in many parts of the somatosensory pathway or other supraspinal areas. The cortical findings indicate a neurobiological component for at least part of the symptoms in patients presenting with nondermatomal somatosensory deficits.
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Pregabalin for the treatment of postherpetic neuralgia: a randomized, placebo-controlled trial.