Obstetrics and gynecology
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Obstetrics and gynecology · May 2005
Comparative StudyChanges in fetal position during labor and their association with epidural analgesia.
To evaluate whether epidural analgesia is associated with a higher rate of abnormal fetal head position at delivery. ⋯ Fetal position changes are common during labor, with the final fetal position established close to delivery. Our demonstration of a strong association of epidural with fetal occiput posterior position at delivery represents a mechanism that may contribute to the lower rate of spontaneous vaginal delivery consistently observed with epidural.
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Obstetrics and gynecology · May 2005
Comparative StudyLow-molecular-weight heparin (dalteparin) in women with gynecologic malignancy.
To compare the efficacy of dalteparin, a low-molecular-weight heparin, to unfractionated heparin (UFH) in the prevention of deep venous thrombosis (DVT) and pulmonary embolism in patients after surgery for gynecologic malignancy. ⋯ The low-molecular-weight heparin dalteparin dosed 5,000 U daily is inadequate postoperative prophylaxis in women undergoing surgery for gynecologic cancer. In addition, heparin administered every 8 hours was not associated with increased bleeding complications. The use of dalteparin at the doses used in this study should be questioned until a large randomized trial shows efficacy in these high-risk patients.