Obstetrics and gynecology
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Obstetrics and gynecology · Mar 2005
Randomized Controlled Trial Comparative Study Clinical TrialOutpatient misoprostol compared with dinoprostone gel for preinduction cervical ripening: a randomized controlled trial.
To determine whether a single outpatient dose of intravaginal misoprostol (versus intracervical dinoprostone gel) reduces the oxytocin use for induction. Despite the numerous trials examining misoprostol for induction, the efficacy of a single outpatient dose of misoprostol followed by oxytocin induction is unknown. ⋯ A single dose of misoprostol administered in the outpatient setting significantly decreases oxytocin use, largely due to labor within the ripening period.
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Obstetrics and gynecology · Mar 2005
Antibiotic prophylaxis and non-group B streptococcal neonatal sepsis.
To assess the effect of increased use of intravenous penicillin for group B streptococcus (Streptococcus agalactiae, GBS) antibiotic prophylaxis on non-GBS neonatal sepsis and antibiotic resistance. ⋯ Institution of a protocol for GBS antibiotic prophylaxis significantly decreased the rate of GBS neonatal sepsis but did not increase the rate of non-GBS neonatal sepsis. Antibiotic resistance patterns of these organisms were not affected.
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Obstetrics and gynecology · Mar 2005
Case ReportsHerceptin (trastuzumab) therapy during pregnancy: association with reversible anhydramnios.
Herceptin (trastuzumab), a new a chemotherapeutic agent, is a monoclonal antibody that blocks the human epidermal growth factor receptor 2 protein. There is no reported experience with use of this agent during pregnancy and possible effects on the fetus. ⋯ Although listed as a category B drug, experience with Herceptin in human pregnancy is limited, and it should be used with caution. Investigation of the role of human epidermal growth factor receptor 2 protein in the embryonic kidney may further our understanding of amniotic fluid dynamics.
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Micturition syncope is a relatively uncommon cause of sudden and temporary loss of consciousness. Most prevalent in older males, this condition is extremely rare in women. ⋯ Micturition syncope during pregnancy may not be a rare occurrence. This potentially dangerous condition is amenable to voiding behavior modification measures.
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Obstetrics and gynecology · Mar 2005
Using an electronic medical record to improve communication within a prenatal care network.
In 2002, the Institute of Medicine called for the introduction of information technologies in health care settings to improve quality of care. We conducted a review of hospital charts of women who delivered before and after the implementation of an intranet-based computerized prenatal record in an inner-city practice. Our objective was to assess whether the use of this record improved communication among the outpatient office, the ultrasonography unit, and the labor floor. ⋯ The use of a paperless, hospital intranet-based prenatal chart significantly improves communication among providers.