Respiratory care
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Spurious hypoxemia has been described in case reports during extreme hyperleukocytosis and has led to recommendations for immediate cooling and analysis of arterial blood gases (ABGs). We sought to determine, in samples processed as recommended, the magnitude of spurious hypoxemia in acute leukemia subjects with hyperleukocytosis. ⋯ In subjects with acute leukemia and hyperleukocytosis, despite cooling and quickly analyzing the samples, we observed poor correlation and agreement between SpO2 and SaO2 , unacceptably low for WBC count > 100 × 10(9)/L. Our results suggest that current guidelines may not totally prevent the diagnosis of spurious hypoxemia.
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Observational Study
The Role of Mean Platelet Volume in Chronic Obstructive Pulmonary Disease Exacerbation.
Studies have supported the correlation between mean platelet volume and COPD. However, there are limited data on the relationship between COPD exacerbation and mean platelet volume. We aimed to evaluate the mean platelet volume trend in patients with COPD exacerbation. ⋯ Mean platelet volume may be an inflammatory marker in exacerbation of COPD, and the measurement of mean platelet volume values may be useful for identifying patients who are at increased risk for exacerbations of illness.
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Editorial Comment
Waiting to Exhale: Optimizing Noninvasive Synchrony in COPD?
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Editorial Comment
Circumstances When Arterial Blood Gas Analysis Can Lead Us Astray.