Respiratory care
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The association between dyspnea and mortality has not been demonstrated in the ICU setting. We tested the hypothesis that dyspnea (self-reported respiratory discomfort) or its observational correlates (5-item intensive care Respiratory Distress Observation Scale [IC-RDOS]) assessed on ICU admission would be associated with ICU mortality. ⋯ IC-RDOS, an observational correlate of dyspnea, but not dyspnea itself, was associated with higher mortality in ICU subjects.
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The effect of single- and dual-limb circuits on aerosol delivery during noninvasive ventilation (NIV) in adult models is unclear. ⋯ During NIV, the aerosol delivery was optimal when a vibrating mesh nebulizer was placed between the non-vented mask and 15 cm from the exhalation port in the single-limb circuit or 15 cm from the Y-piece in the inspiratory limb of the dual-limb circuit; no significant difference was found between the two optimal placements. Humidification had little effect on aerosol delivery. Aerosol delivery was poor in the single-limb circuit with a vented mask.
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Adults with chronic lung disease use electronic cigarettes (e-cigarette) at higher rates than those without chronic lung disease. Because e-cigarettes have now been shown to cause adverse pulmonary effects and impair immune responses, it is particularly important to identify the factors that contribute to e-cigarette use in individuals with chronic lung disease. We tested whether mental health explains the association between chronic lung disease and e-cigarette use, and whether the association between chronic lung disease and e-cigarette use is conditional on the presence of respiratory symptoms. ⋯ The association between chronic lung disease and e-cigarette use may be due, in part, to poorer mental health among individuals with chronic lung disease. These findings provide preliminary evidence that improving the mental health of individuals with chronic lung disease could reduce e-cigarette use in this vulnerable population.
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Residual volume (RV) is a derived lung compartment that correlates with air trapping in the context of air flow obstruction on spirometry. The significance of an isolated elevation in RV in the absence of other pulmonary function test (PFT) abnormalities is not well defined. We sought to assess the clinical and radiologic findings associated with isolated elevation in RV. ⋯ Isolated elevation in RV on PFTs is a clinically relevant abnormality associated with airway-centered diseases.
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Critical-care ventilators provide patient circuit compensation (CC) to counteract the loss of volume due to patient circuit compliance. No studies show the effect of inspiratory efforts (indicating maximal value of the muscle pressure waveforms [Pmax]) on CC function. The goal of this study was to determine how Pmax affects volume delivery with or without CC for both volume control continuous mandatory ventilation with set-point targeting scheme (VC-CMVs) and pressure control continuous mandatory ventilation with adaptive targeting scheme (PC-CMVa) modes on the Servo-u ventilator. ⋯ CC corrected the delivered VT for volume lost due to compression in the patient circuit as expected. This compensation volume decreases as airway pressure drops due to patient Pmax.