Anesthesia, essays and researches
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Reduction in central sensitization by gabapentinoids that include gabapentin and pregabalin may reduce acute postoperative pain. ⋯ It is concluded in this study that pregabalin group had lower VAS score, prolonged timing of first rescue analgesic, and less opioids consumption than the gabapentin group. Both gabapentinoids had better postoperative analgesic profile than placebo.