European journal of trauma and emergency surgery : official publication of the European Trauma Society
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Eur J Trauma Emerg Surg · Feb 2020
Increased extracellular ubiquitin in surgical wound fluid provides a chemotactic signal for myeloid dendritic cells.
Myeloid dendritic cells (MDC) decline significantly after multiple traumas which might be due to an increased migration into injured regions. Ubiquitin is released from dying cells and is increased in serum after trauma. Ubiquitin can bind to the chemokine receptor CXCR4. Thus, we hypothesized that elevated ubiquitin provides a chemotactic signal for MDC to injured regions. ⋯ Ubiquitin is increased in SWF and exerts a significant chemotactic effect on MDC. This mechanism might play a role in attraction of immune cells to injured regions and might contribute to the decline of circulating MDC in multiple traumas.
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Eur J Trauma Emerg Surg · Feb 2020
Correction to: Surgeon-performed point-of-care ultrasound for acute cholecystitis: indications and limitations: a European Society for Trauma and Emergency Surgery (ESTES) consensus statement.
Unfortunately, the author Luca Ponchietti was omitted in the original publication. Please find the correct author list here.
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Eur J Trauma Emerg Surg · Feb 2020
The Aberdeen Weight-Bearing Test (Knee): a new objective test for anterior knee discomfort.
We present the Aberdeen Weight-Bearing Test (Knee), an objective test specific for anterior knee discomfort assessed via load bearing. We assess its validity by performing it on normal subjects with no knee symptoms and subjects who had undergone anterograde tibial nailing. ⋯ The Aberdeen Weight-Bearing Test (Knee) is an objective, easily reproducible, specific test for anterior knee discomfort. It produces different results in individuals who have undergone anterograde tibial nailing compared to individuals with no knee symptoms.
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Eur J Trauma Emerg Surg · Feb 2020
Digital templating without a calibration marker is accurate at predicting implant size for hip hemiarthroplasty.
This study aims to assess the accuracy of digital templating for hip hemiarthroplasty using radiographs without calibration. ⋯ Digital templating of radiographs without calibration can be used to accurately and reliably predict femoral head size and offset at a set magnification of 120%. Femoral stem size, however, is more difficult to template adequately on pre-operative radiographs without calibration.
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Eur J Trauma Emerg Surg · Feb 2020
Mesenchymal stem cell transplantation in polytrauma: Evaluation of bone and liver healing response in an experimental rat model.
Trauma is the most common cause of death of young people in the world. As known, mesenchymal stem cells (MSCs) accelerate tissue regeneration mechanisms. In our study, we aimed to investigate the effects of MSCs transplantation on the healing of liver and bone tissue by considering trauma secondary inflammatory responses. ⋯ Herewith we have shown that MSC infusion in posttraumatic rats leads to less aggressive and more effective consequences on liver and bone tissue healing. Human MSC treatment for trauma is still in early stages of development; thus standard protocols, and patient inclusion criteria should be established beforehand clinical trials.