BMC anesthesiology
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Randomized Controlled Trial
Efficacy and safety of remimazolam tosilate in anesthesia for short otolaryngology surgery.
Remimazolam tosilate represents the novel ultrashort-acting benzodiazepine drug. This work focused on exploring whether remimazolam tosilate was effective and safe in anesthesia for short otolaryngology surgery in adults, and optimize its medication regimen, thus providing a theoretical basis for its widespread clinical application. ⋯ Remimazolam tosilate is effective on anesthesia for short otolaryngology surgery. Remimazolam shows the rapid onset, stable circulation, fast postoperative recovery, no increase in perioperative AEs, and high satisfaction with anesthesia experience compared with midazolam.
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Randomized Controlled Trial
Effect of intravenous lidocaine on catheter‑related bladder discomfort, postoperative pain and opioid requirement in complex fusion lumbar spinal surgery: a randomized, double blind, controlled trial.
Catheter-related bladder discomfort (CRBD) and pain commonly arises postoperatively in patients who undergo intra-operative urinary catheterization. The study aims to demonstrate the effectiveness of intravenous lidocaine to prevent CRBD and postoperative pain in complex lumbar spinal surgery. ⋯ Intravenous lidocaine administration significantly reduced the incidence of moderate-to-severe CRBD at PACU and at 1 h postoperatively. Additionally, its use in complex spine surgery led to reductions in postoperative pain, opioid requirement, and improved patient satisfaction, without any observed side effects.
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High spinal block is a serious complication of spinal anesthesia. However, findings regarding its associated risk factors are inconsistent, and no studies have reported a relevant risk prediction score. We aimed to determine the risk prediction score for high spinal block in patients who were induced spinal anesthesia for cesarean delivery. ⋯ The combination of patient- and anesthesia-related predictors played an important role in the intermediate- and high-risk groups for high sensory spinal block. Addressing the modifiable risk factors-a GA < 35 weeks, an optimal dose of bupivacaine, and the experience level of the spinal block performer-could minimize the risk of high spinal block during cesarean delivery.
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Randomized Controlled Trial Comparative Study
Comparison of bougie-guided cricothyrotomy and traditional cricothyrotomy techniques in an obese 3D-printed surgical airway manikin: a randomized controlled study.
Obesity is one of the conditions that may require invasive airway management. The effectiveness of invasive airway techniques in obesity is not fully understood, and there is no routinely recommended technique. This study aimed to compare the first attempt success rate, procedure time, and difficulty of traditional surgical cricothyrotomy and bougie-guided cricothyrotomy on a 3D-printed surgical airway manikin made obese using simple techniques. ⋯ The manuscript has been presented 9th EurAsian Congress on Emergency Medicine (oral presentation) at the 9-12 November, 2023, Antalya, Turkey, and won the best oral abstract award at this congress.
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Randomized Controlled Trial Comparative Study
Comparative efficacy of ciprofol and propofol in reducing respiratory depression during ERCP anesthesia: a randomized controlled trial.
Propofol is one of the important drug causes of respiratory depression in endoscopic retrograde cholangiopancreatography (ERCP) anesthesia. This study aims to clarify whether Ciprofol in ERCP anesthesia reduces the respiratory depression rate. ⋯ For patients undergoing anesthesia for ERCP, Ciprofol, compared to Propofol, has been shown to effectively reduce the incidence of intraoperative respiratory depression, thereby enhancing the safety of the anesthesia process.