Masui. The Japanese journal of anesthesiology
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A newborn female infant born at 41 week gestation with Nager acrofacial dysostosis had no congenital abnormalities in her parents and closed relatives. Her mother had uncomplicated pregnancy and normal delivery. ⋯ A laryngeal mask was placed after several trials of intubation, and ventilation was carried out successfully. We consider that the use of a laryngeal mask is one of the best ways in a case of difficult intubation.
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We measured the density and specific gravity at room (20 degrees C) and body (37 degrees C) temperatures of spinal anesthetic solutions, which have been commercially prepared in Japan. Solutions investigated were; (1) 0.4 % and 0.5 % tetracaine (T) in water, 0.5 % T in normal saline, 5 % glucose and 10 % glucose, (2) 0.3 % dibucaine in 5 % sodium chloride: (P), (3) 0.24 % dibucaine with 0.12 % tetracaine in 9.5 % glucose: (N); (4) 3 % lidocaine in 8.5 % glucose: (X); and (5) 0.5 % bupivacaine in water containing preservatives: (M). We also determined the density and specific gravity of normal human cerebrospinal fluid (CSF) in Japanese (n = 10) at 37 degrees C. ⋯ Thirty seven centigrade 0.5 % T in normal saline and 37 degrees C 0.5 % M in water had the density comparable to 37 degrees C human CSF and were considered to be relatively isobaric solutions. Our data demonstrated that human CSF had various densities. Therefore, it is possible that these isobaric solutions would vary their pharmacodynamic profiles in intrathecal use according to individual CSF characteristics and temperature of the solution.
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We have assessed the deleterious effects of methyl methacrylate (MMA) on cardiac function and metabolism in the isolated heart-lung preparation and their protection by ulinastatin. Twenty-four male Wistar rats were prepared for the heart-lung model. They were randomly divided into 3 groups. ⋯ MMA 1000 micrograms.ml-1 is much higher than the blood level (0.05-31.89 micrograms.ml-1) reported clinically in patients who had femoral prosthesis. Ulinastatin increased myocardial glycogen content which had been reduced by MMA. This may suggest that ulinastatin has a protective effect on heart damaged by MMA.