Masui. The Japanese journal of anesthesiology
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Case Reports
[High epidural anesthesia for asthmatic patients--case reports and philological Investigation].
The author experienced anesthetic management of three chronic asthmatic patients for emergency or scheduled lower intraperitoneal operations. The patients were operated under high epidural anesthesia with upper level of T2, in the same way as non-asthmatic patients scheduled for the same lower abdominal operations. ⋯ Conversely, there were many asthmatic patients reported who had been relieved of attacks or whose symptoms and signs had not been changed by thoracic sympathetic blockade including epidural anesthesia. At the present time, neurohumoral innervation of the lungs remains to be elucidated, and it would be overhasty to conclude that epidural anesthesia is contraindicated in asthmatic patients.
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We studied the effects of repeated low-flow sevoflurane anesthesia for 6 hours. Five beagle dogs received 1.3 MAC (3%) sevoflurane anesthesia. Anesthesia of 6 hours was repeated on at the 7th day after the first anesthesia. ⋯ No significant changes in other blood chemistry studies were observed. The excretion of renal tubular enzymes did not increase during and after anesthesia. Repeated low flow sevoflurane anesthesia in beagles did not affect hepatic and renal function significantly.