Acta anaesthesiologica Belgica
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In 150 patients buprenorphine was given as postoperative analgesic in a dose of 4 microgram/kg. Pain suppression was judged very good (71%), fairly good (24%) and insufficient (5%). Analgesic activity lasted at least 325 +/- 15 min. Side effects were few.
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Acta Anaesthesiol Belg · Jan 1976
Comparative StudyA comparative study of etomidate and methohexital as induction agents for analgesic anesthesia.
Two hundred current surgical procedures were done in adult patients using neuroleptanalgesia with either methohexital (1 mg/kg) or etomidate induction (0.3 mg/kg) in half of the cases. The cardiovascular function was less altered with etomidate (less occurrence of tachycardia, blood pressure drops or systolo-diastolic pinching). The etomidate dosage chosen more often gave an immediate satisfactory sleep. ⋯ Without these precautions, myoclonia can occur in two-thirds of the patients. However, these myoclonia are bothersome and of prolonged duration in rare instances and would be of real annoyance only when this drug would be used alone for surgical procedures of short duration where perfect patient immobility is required. We therefore conclude and confirm that etomidate is a good induction agent for neuroleptanalgesia anesthesia procedures.