Acta anaesthesiologica Belgica
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Acta Anaesthesiol Belg
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Acta Anaesthesiol Belg · Jan 2001
Clinical interpretation of pharmacokinetic and pharmacodynamic propofol-opioid interactions.
This manuscript describes the pharmacokinetic and pharmacodynamic interactions between propofol and the opioids. ⋯ The proper exploration and use of published pharmacokinetic and pharmacodynamic interaction data allows the clinical anaesthesiologist to optimise the clinical administration of propofol and the various opioids when given alone or in combination.