Revista española de anestesiología y reanimación
-
Rev Esp Anestesiol Reanim · Jan 1994
Randomized Controlled Trial Comparative Study Clinical Trial[Effects on the newborn infant of thiopental and propofol used in anesthetic induction in cesarean section].
To compare the effects of an anesthetic induction dose of thiopental to that of propofol on the vitality of the neonate, as measured by Apgar score and the interval between extraction of the newborn and unassisted respiration. ⋯ If the induction-extraction interval is 10 min or less, both thiopental (4 mg/kg) and propofol (2 mg/kg) given in a single dose for induction of general anesthesia in all types of cesarean section are equally safe for the newborn infant.
-
Rev Esp Anestesiol Reanim · Jan 1994
Comparative Study[Speed of intubation using a new neuromuscular blocker. Rocuronium bromide (ORG 9426)].
To compare intubation conditions and neuromuscular parameters, patency time, maximum level of block, time and clinical duration of effect for rocuronium bromide 0.6 mg/kg (ORG 9426) versus equally potent doses of vecuronium and atracurium under similar experimental conditions. ⋯ Means of onset times and times of effect for rocuronium (33 and 135 sec) were significantly lower than those obtained with vecuronium and atracurium. Clinical duration, free of hemodynamic changes, was similar in the three groups. Rocuronium produces excellent intubation conditions 60 sec after administration, although at this point peripheral muscle block was only partial. Rocuronium may be superior to other neuromuscular blockers available today as a result of the speed with which it affords excellent intubation conditions.
-
Rev Esp Anestesiol Reanim · Jan 1994
[Effect of propofol on oxygenation and the pulmonary short-circuit during single-lung ventilation].
To determine the effect of propofol on pulmonary short circuit or shunt (Qs/Qt). ⋯ Continuous infusion of propofol produces a significant increase of Qs/Qt and a significant decrease of PaO2 during single-lung ventilation for thoracic surgery.